Results 41 to 50 of about 1,032,590 (316)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Food insecurity and associated depression among older adults in India: evidence from a population-based study

open access: yesBMJ Open, 2022
Objective The present study aimed to examine the associations of several indicators of food insecurity with depression among older adults in India.Design A cross-sectional study was conducted using country-representative survey data.Setting and ...
Shobhit Srivastava   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A Fast Approach to Scale Up Disk Arrays With Parity Declustered Data Layout by Minimizing Data Migration

open access: yesIEEE Access, 2019
Parity declustering is widely deployed in erasure-coded storage systems so as to provide fast recovery and high data availability. However, to perform scaling on such redundant array of inexpensive disks (RAIDs), it is necessary to preserve parity ...
Zhipeng Li   +4 more
doaj   +1 more source

Objectivity Data Migration

open access: yes, 2003
Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 7 pages, PDF.
Nowak, Marcin   +4 more
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Match between soaring modes of black kites and the fine-scale distribution of updrafts

open access: yesScientific Reports, 2017
Understanding how soaring birds use updrafts at small spatial scales is important to identify ecological constraints of movement, and may help to prevent conflicts between wind-energy development and the conservation of wildlife.
Carlos D. Santos   +6 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Expert consensus on a protocol for conducting bibliometric analysis of scientific articles on global migration health (GMH)

open access: yesBMJ Open
Background Migration and health are key priorities in global health and essential for protecting and promoting the health of migrants. To better understand the existing evidence on migration health, it is critical to map the research publication activity
  +22 more
doaj   +1 more source

Closing disparities between European sending and receiving international migration flow data

open access: yesRegional Studies, Regional Science, 2022
Evidence-based policies to monitor and manage migration flows require accurate data. Data collection on international migration flow statistics is based on a range of data sources and measures.
Guy J. Abel, Dilek Yildiz
doaj   +1 more source

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