Results 181 to 190 of about 23,785,135 (371)

Defect Engineering Activates Pyrene‐Based Covalent Organic Frameworks for Efficient Photocatalytic Uranium Capture

open access: yesAdvanced Science, EarlyView.
A defect‐engineered pyrene‐based covalent organic framework (TP‐PYTO‐SA) is developed via strategic salicylaldehyde incorporation. This approach simultaneously enhances hydrophilicity and introduces uranyl coordination sites, while optimized defect density significantly improves charge separation.
Weikun Yao   +5 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma   +15 more
wiley   +1 more source

Data Mining

open access: yesInternational Journal for Research in Applied Science and Engineering Technology, 2021
openaire   +1 more source

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