Results 81 to 90 of about 243,501 (262)

Joint Bayesian Stochastic Inversion of Well Logs and Seismic Data for Volumetric Uncertainty Analysis [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2015
Here in, an application of a new seismic inversion algorithm in one of Iran’s oilfields is described. Stochastic (geostatistical) seismic inversion, as a complementary method to deterministic inversion, is perceived as contribution combination of ...
Moslem Moradi   +4 more
doaj  

Socioeconomic disparities in prevalence, awareness, treatment, and control of hypertension over the life course in China

open access: yesInternational Journal for Equity in Health, 2017
Background The socioeconomically disadvantaged populations are more likely to suffer from hypertension, and few have effectively treated and controlled their hypertension.
Fan Yang   +4 more
doaj   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

open access: yesAdvanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu   +4 more
wiley   +1 more source

Recent Advances in Decoupling Strategies for Soft Sensors

open access: yesAdvanced Science, EarlyView.
This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan   +4 more
wiley   +1 more source

Uncertainty Inspired Early Autism Spectrum Disorder Screening via Contrastive Image-Viewing Paradigm

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Eye-tracking technology is found effective in revealing the specific visual preference of Autism Spectrum Disorder (ASD) which can be characterized by high systemizing and low empathizing abilities.
Ying Zhang   +8 more
doaj   +1 more source

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

open access: yesAdvanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing   +10 more
wiley   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

open access: yesAdvanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li   +16 more
wiley   +1 more source

Life cycle benzophenone 1 exposure induces anxiety- and depression-like behaviors in zebrafish via endoplasmic reticulum stress-mediated dopaminergic system dysfunction

open access: yesEnvironmental Chemistry and Ecotoxicology
Environmental exposure to benzophenones (BPs) has emerged as a potential risk factor for the comorbidity of anxiety and depression. Among them, BP1 has attracted increasing attention due to its potential neurotoxic effects.
Zhipeng Qi   +12 more
doaj   +1 more source

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