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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A model specification test for semiparametric nonignorable missing data modeling. [PDF]
Econom StatTang CY.
europepmc +1 more source
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Common Data Model for Healthcare Data
2018 9th International Conference on Computing, Communication and Networking Technologies (ICCCNT), 2018There is a huge volume of data made openly available to the masses on Government data sites such as the www.data.gov.in. However, it is very difficult to make sense between data from two different data sets or different domains. As a result a lot of time is spent in just collecting and linking this data from various sources before it can be put to use.
Umair M. Khan +3 more
openaire +1 more source
Multidimensional data modeling for complex data
Proceedings 15th International Conference on Data Engineering (Cat. No.99CB36337), 1999Online Analytical Processing (OLAP) systems considerably ease the process of analyzing business data and have become widely used in industry. Such systems primarily employ multidimensional data models to structure their data. However current multidimensional data models fall short in their abilities to model the complex data found in some real world ...
Torben Bach Pedersen +1 more
openaire +2 more sources
Data modeling styles in data warehousing
2014 37th International Convention on Information and Communication Technology, Electronics and Microelectronics (MIPRO), 2014The paper presents a coordinated set of data modeling styles relevant for data warehouse design in the context of relational databases. The scope of presented models covers: a) entity relationship models of existing relational DB sources, b) logical data vault model for integrated enterprise data warehouses as a system of records, c) dimensional fact ...
Vladan M. Jovanovic +2 more
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2009
The Grid allows scientists to design and perform very large-scale experiments that are not possible previously. Many of these experiments produce a large number of data sets and significantly the amount of data being captured, generated, replicated and archived is growing at an astonishing rate.
Tim Ho, David Abramson 0001
openaire +4 more sources
The Grid allows scientists to design and perform very large-scale experiments that are not possible previously. Many of these experiments produce a large number of data sets and significantly the amount of data being captured, generated, replicated and archived is growing at an astonishing rate.
Tim Ho, David Abramson 0001
openaire +4 more sources
2021
Time is an essential dimension of our perception of the world and hence an important dimension for the representation of the real and social world in data models. We give an overview of the basics of representing time in data models and representing objects and processes with respect to the temporal dimension.
Johann Eder +2 more
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Time is an essential dimension of our perception of the world and hence an important dimension for the representation of the real and social world in data models. We give an overview of the basics of representing time in data models and representing objects and processes with respect to the temporal dimension.
Johann Eder +2 more
openaire +1 more source
Information Systems, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jake Yue Chen, John V. Carlis
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jake Yue Chen, John V. Carlis
openaire +3 more sources
Proceedings of the 2007 ACM symposium on Applied computing, 2007
As a sub-type of ncRNA genes, micro RNA (miRNA) produces RNA that is implicated in the regulation of gene translation and expression. Human diseases can result from alternation in such non-coding RNA. Building a consolidated miRNA database repository thus becomes a crucial element for miRNA-related research. We have set up a dual objective in our work:
Sarah Lopez, Guoqing Lu, Zhengxin Chen
openaire +1 more source
As a sub-type of ncRNA genes, micro RNA (miRNA) produces RNA that is implicated in the regulation of gene translation and expression. Human diseases can result from alternation in such non-coding RNA. Building a consolidated miRNA database repository thus becomes a crucial element for miRNA-related research. We have set up a dual objective in our work:
Sarah Lopez, Guoqing Lu, Zhengxin Chen
openaire +1 more source