Results 91 to 100 of about 2,612,468 (303)

Maintenance strategy optimisation for infrastructure assets through cost modelling [PDF]

open access: yes, 2013
In infrastructure asset management, maintenance strategies in terms of cost modelling is normally adopted to achieve two broad strategic objectives: to ensure that sufficient funding is available to maintain the portfolio of assets; and to ensure that a ...
Gang, Yi, Wang, Wenbin, Zhang, Wenjuan
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Temporal Bayesian classifiers for modelling muscular dystrophy expression data [PDF]

open access: yes, 2006
The analysis of microarray data from time-series experiments requires specialised algorithms, which take the temporal ordering of the data into account. In this paper we explore a new architecture of Bayesian classifier that can be used to understand how
Hoen, PAC't   +3 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Data issues in general equilibrium modelling [PDF]

open access: yes
In recent years global general equilibrium (GE) models have been used to analyse policy issues such as trade liberalisation, regional integration and environmental policies.
Beutre, Benjamin   +2 more
core   +1 more source

Application of Computational Intelligence Techniques to Process Industry Problems [PDF]

open access: yes, 2008
In the last two decades there has been a large progress in the computational intelligence research field. The fruits of the effort spent on the research in the discussed field are powerful techniques for pattern recognition, data mining, data modelling,
Gabrys, Bogdan, Kadlec, Petr
core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Generalized bi-additive modelling for categorical data [PDF]

open access: yes
Generalized linear modelling (GLM) is a versatile technique, which may be viewed as a generalization of well-known techniques such as least squares regression, analysis of variance, loglinear modelling, and logistic regression.
Groenen, P.J.F., Koning, A.J.
core   +1 more source

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