Results 131 to 140 of about 32,466,082 (318)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Confronting models with data

open access: yesJournal of Hospital Infection, 2007
Until now, most of the mathematical modelling work on nosocomial infections has used simple models that have permitted qualitative, but not reliable quantitative predictions about the likely effect of different interventions. Increasingly, researchers would like to use models to provide reliable quantitative answers to both scientific and policy ...
openaire   +2 more sources

Atmospheric transmission models for FIFI-LS: altitude 38kft, 39deg O3

open access: yes
This dataset contains atmospheric transmission models calculated by a modified version of ATRAN ("SDC ATRAN"). They are to be used as the default models for FIFI-LS data reduction with SOFIA Redux The models are generated from a modified "SDC ATRAN ...
SOFIA Data Center
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Atmospheric transmission models for FIFI-LS: altitude 39kft, 39deg O3

open access: yes
This dataset contains atmospheric transmission models calculated by a modified version of ATRAN ("SDC ATRAN"). They are to be used as the default models for FIFI-LS data reduction with SOFIA Redux The models are generated from a modified "SDC ATRAN ...
SOFIA Data Center
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A Review of Data Models and Frameworks in Urban Environments in the Context of AI

open access: yesUrban Science
This review paper provides a comprehensive review and analysis of the research and practice literature relating to data models and frameworks pertaining to urban and other AI-rich environments, extending to the planetary environment.
H. Patricia McKenna
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Abstracts From the 2024 Health Care Systems Research Network (HCSRN) Annual Conference, Milwaukee, Wisconsin

open access: yesJournal of Patient-Centered Research and Reviews
The Health Care Systems Research Network (HCSRN) comprises 20 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Health Care Systems Research Network
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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