Results 111 to 120 of about 26,006,190 (296)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Collaborative Data-Plane and Control-Plane Architecture for Real-Time Anomaly Detection
IEEE AccessProgrammable data planes enable real-time traffic monitoring and line-rate response. However, their limited computational capabilities restrict deep packet inspection.
Xiao Tian +5 more
doaj +1 more source
Defeating Data Plane Attacks With Program Obfuscation
IEEE Transactions on Dependable and Secure ComputingData plane switches in software-defined networks are increasingly recognised as potential targets for attack, with recent exploits showing their vulnerability to full compromise. The serious consequences of such a breach have prompted the design of compromise detection mechanisms, which monitor switch forwarding behaviour at runtime to ensure that it ...
Conor Black, Sandra Scott-Hayward
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Plane Quasar Survey: First Data Release
The Astrophysical Journal Supplement SeriesWe present a sample of 305 QSO candidates having ∣ b ∣ < 30°, the majority with GALEX magnitudes near-UV < 18.75. To generate this sample, we apply UV–IR color selection criteria to photometric data from the Ultraviolet Galactic Plane Survey as part of ...
Jessica Werk +6 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Semilinear equations in the plane with measurable data
Доповiдi Нацiональної академiї наук УкраїниWe study semilinear partial differential equations in the plane, the linear part of which is written in a divergence form. The main result is given as a factorization theorem.
V.Ya. Gutlyanskiĭ +2 more
doaj +1 more source
, 2017 My blog post about how to fit a plane to data: https://dfm.io/posts/fitting-a-plane/
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source