Results 231 to 240 of about 2,559,985 (286)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Performance of a GPU- and time-efficient pseudo-3D network for magnetic resonance image super-resolution and motion artifact reduction. [PDF]

Sci Rep
Li H, Liu J, Schell M, Huang T, Lauer A, Schregel K, Jesser J, Vollherbst DF, Bendszus M, Heiland S, Hilgenfeld T.   +10 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Test-Retest Reliability and Validity of a Sums-of-Gaussians-Based Markerless Motion Capture System for Human Lower-Limb Gait Kinematics. [PDF]

Bioengineering (Basel)
Shou Y, Gao C, Xi C, Jia J, Lü J, Fang Y, Lin C, Liang Z.   +7 more
europepmc   +1 more source

Utilization of the posterior iliac line for visualizing posterior column screws in obturator oblique view. [PDF]

PLoS One
Li H, Xu L, An L, Li X, Zhang L, Liu J, Zhai K, Sun X, Feng N.   +8 more
europepmc   +1 more source

Comment on: Ultrasound-guided erector spinae plane block vs modified thoracolumbar interfascial plane block in lumbar spine surgeries. [PDF]

Saudi J Anaesth
Kurhekar P, Narayanan S, Rajarathinam B.
europepmc   +1 more source

Multi-plane vision transformer for hemorrhage classification using axial and sagittal MRI data. [PDF]

Sci Rep
Das BK, Zhao G, Mailhe B, Re TJ, Comaniciu D, Gibson E, Maier A.   +6 more
europepmc   +1 more source

Validation and Reproducibility of an App for Continuous Measurement as an Assessment Tool for Idiopathic Scoliosis. [PDF]

Sensors (Basel)
Navarro IJRL, Jacob L, Masetto K, Dulio F, Negrini A, Negrini S, Zaina F, Negrini A.   +7 more
europepmc   +1 more source

Comment on: "Analgesic effects of bilateral ultrasound-guided erector spinae plane block versus patient-controlled intravenous analgesia in correction surgery for idiopathic scoliosis: study protocol for a randomized controlled trial". [PDF]

Perioper Med (Lond)
Sethuraman RM.
europepmc   +1 more source