Results 71 to 80 of about 25,313 (297)

Leveraging the Big Data Produced by the Network to Take Intelligent Decisions on Flow Management

open access: yesIEEE Access, 2018
Software-defined network (SDN) offers a very advantageous feature of programming the network at run time by decoupling the control plane from data plane to have centralized and better forwarding decisions.
Shafaan Khaliq Bhatti   +5 more
doaj   +1 more source

Mathematical Programming for Data Mining: Formulations and Challenges

open access: yes, 1998
This paper is intended to serve as an overview of a rapidly emerging research and applications area. In addition to providing a general overview, motivating the importance of data mining problems within the area of knowledge discovery in databases, our
Fayyad, Usama M.   +7 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Malicious Traffic Detection on Tofino Using Graph Attention Model

open access: yesApplied Sciences
With the surge of malicious traffic in networks, existing detection methods struggle to balance real-time performance and efficiency. Data plane programmability, as an emerging technology, offers rapid control loops that can more effectively detect and ...
Xichang Gao   +4 more
doaj   +1 more source

Zero-one IP problems: Polyhedral descriptions & cutting plane procedures

open access: yes, 1994
A systematic way for tightening an IP formulation is by employing classes of linear inequalities that define facets of the convex hull of the feasible integer points of the respective problems.
Mitra, G, Yarrow, L, Abdul-Hamid, F
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

P4 Cybersecurity Solutions: Taxonomy and Open Challenges

open access: yesIEEE Access
The field of cybersecurity has witnessed a significant shift towards Programmable Data Planes with the emergence of the P4 programming P4. The existing literature lacks a comprehensive taxonomy that provides collaborative classifications and ...
Christian Garzon   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Securing IoT Against Slow-Rate DDoS Attacks: Implementation With Tofino P4 ASIC Hardware

open access: yesIEEE Access
DDoS attacks are relevant threats that continue to grow in number, power, and complexity. These attacks are not only materialized through stealthy and fast variants in different network layers but also adapt their behavior and objectives, increasingly ...
Erick D. Ramirez-Martinez   +4 more
doaj   +1 more source

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