Results 121 to 130 of about 6,519,550 (284)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Course, Counselor, and Teacher Gaps: Addressing the College Readiness Challenge in High Poverty High Schools [PDF]
, 2015 This paper presents a new analysis of education data on high schools in the 100 largest school districts that highlights the role of inadequate K-12 preparation as a barrier to postsecondary success for students who live in poverty.
Rhoda Bryant
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Preparing the bound instance of quantum entanglement
, 2011 Among the possibly most intriguing aspects of quantum entanglement is that it comes in "free" and "bound" instances. Bound entangled states require entangled states in preparation but, once realized, no free entanglement and therefore no pure maximally ...
DiGuglielmo, J. +5 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Predicting hydration layers on surfaces using deep learning. [PDF]
Nanoscale Adv, 2021 Ranawat YS, Jaques YM, Foster AS.
europepmc +1 more source
Analysis of MAGSAT data of the Indian region [PDF]
Progress in the development of software for reading MAGSAT data tapes and for the reduction of anomaly data, and in the preparation of data for magnetic anomaly maps is ...
Agarwal, B. N. P. +8 more
core +1 more source
Individual Nurse Productivity in Preparing Patients for Discharge Is Associated with Patient Likelihood of 30-Day Return to Hospital [PDF]
, 2019 Objective: Applied to value-based health care, the economic term “individual productivity” refers to the quality of an outcome attributable through a care process to an individual clinician.
Bang, James +7 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source