Results 101 to 110 of about 23,477,104 (364)

Innovation under pressure: Implications for data privacy during the Covid-19 pandemic

open access: yesBig Data & Society, 2020
The global Covid-19 pandemic has resulted in social and economic disruption unprecedented in the modern era. Many countries have introduced severe measures to contain the virus, including travel restrictions, public event bans, non-essential business ...
G. Newlands   +5 more
semanticscholar   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Literature data-based de novo candidates for drug repurposing

open access: yesBMC Bioinformatics
Background Drug repurposing offers a promising strategy for drug discovery. Drug repurposing involves identifying new therapeutic indications for existing, marketed drugs, thereby reducing the risks, costs, and time typically required for drug ...
Xianglong Liang, Xin Jiang, Yifang Ma
doaj   +1 more source

Big Privacy: Challenges and Opportunities of Privacy Study in the Age of Big Data

open access: yesIEEE Access, 2016
One of the biggest concerns of big data is privacy. However, the study on big data privacy is still at a very early stage. We believe the forthcoming solutions and theories of big data privacy root from the in place research output of the privacy ...
Shui Yu
doaj   +1 more source

Data Anonymization Using Pseudonym System to Preserve Data Privacy

open access: yesIEEE Access, 2020
Data collection and storage in a large size is done on a routine basis in any company or organization. To this end, wireless network infrastructure and cloud computing are two widely-used tools.
Shukor Abd Razak   +2 more
semanticscholar   +1 more source

Personal Privacy and Common Goods: A Framework for Balancing Under the National Health Information Privacy Rule [PDF]

open access: yes, 2002
In this Article, we discuss how these principles for balancing apply in a number of important contexts where individually identifiable health data are shared. In Part I, we analyze the modern view favoring autonomy and privacy.
Gostin, Lawrence O.   +1 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Privacy preservation techniques in big data analytics: a survey

open access: yesJournal of Big Data, 2018
Incredible amounts of data is being generated by various organizations like hospitals, banks, e-commerce, retail and supply chain, etc. by virtue of digital technology.
P. Ram Mohan Rao   +2 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

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