Results 131 to 140 of about 552,298 (314)
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
Enhancing Metric Privacy With a Shuffler [PDF]
International audienceDifferential Privacy (DP) is one of the most successful privacy-preserving frameworks. In the central model of DP a trusted server adds controlled noise as it acts as an interface between the data providers (users) and the data ...
Chatzikokolakis, Konstantinos +2 more
core +2 more sources
Noiseless Privacy-Preserving Decentralized Learning [PDF]
Decentralized learning (DL) enables collaborative learning without a server and without training data leaving the users' devices. However, the models shared in DL can still be used to infer training data.
Biswas, Sayan +6 more
core +2 more sources
Wormhole Whispers: Reflecting User Privacy Data Boundaries Through Algorithm Visualization
Applied SciencesAs user interactions on online social platforms increase, so does the public’s concern over the exposure of user privacy data. However, ordinary users often lack a clear and intuitive understanding of how their personal online information flows and how ...
Xiaoxiao Wang +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman +5 more
wiley +1 more source
Survey of differentially private methods for trajectory data
网络与信息安全学报With the rapid development of sensor and positioning technologies, vast amounts of trajectory data were generated, stored, and shared by users’ smart mobile devices.
SUN Xinyue +3 more
doaj