Results 111 to 120 of about 7,233,032 (341)
Improving Both Quantity and Quality: Incentive Mechanism for Social Mobile Crowdsensing Architecture
IEEE Access, 2018 Mobile crowdsensing has emerged as an efficient paradigm for performing large-scale sensing tasks. Improving both the quantity and quality of users is still the pivotal problem for mobile crowdsensing system.
Jia Xu +4 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Signal processing methods for EEG data classification [PDF]
, 2008 Imperial Users ...
Varnavas, Andreas Soteriou +1 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A machine-learning approach to thunderstorm forecasting through post-processing of simulation data [PDF]
, 2023 Kianusch Vahid Yousefnia +3 more
openalex +1 more source
Data processing large quantities of multispectral information [PDF]
, 1975 Method is combination of digital and optical techniques. Multispectral data is coded into binary matrix format and then encoded onto photographic film. Film is holographically correlated with spectral signature to generate single-class classification map.
Haskell, R. E.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Real-Time Data Processing With Lambda Architecture [PDF]
, 2019 Data has evolved immensely in recent years, in type, volume and velocity. There are several frameworks to handle the big data applications. The project focuses on the Lambda Architecture proposed by Marz and its application to obtain real-time data ...
Malusare, Omkar Ashok
core +1 more source