Results 121 to 130 of about 335,380 (266)

Flexible, super-resolution skin with in-sensor hyperdimensional computing for real-time pressure field perception. [PDF]

Sci Adv
Zhang F, Xu Z, Hou C, Yin L, Yin M, Lian M, He W, Li S, Cheng P, Huang Y.   +9 more
europepmc   +1 more source

Using natural language processing to facilitate the harmonization of mental health questionnaires: a validation study using real-world data Lecturer in Psychology Professor of Computer Science Associate professor Pesquisador pós-doutor Newton Fellow

Pooling data from different sources may help further mental health research by providing larger sample sizes and allowing cross-study comparisons; however, the heterogeneity in how variables are measured across studies poses a significant challenge to this process.
Eoin McElroy, Raymond Bond, Maurice D Mulvenna, Mark Shevlin, George Ploubidis, Mauricio Scopel Hoffmann, Bettina Moltrecht   +6 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The total eclipse of bioinformatics: From disruption to convention, and a gentle warning. [PDF]

PLoS Comput Biol
Ouzounis CA.
europepmc   +1 more source

Study of IA methods in data analytics (machine learning / deep learning) to improve the content of computer science MOOCs and contribution to the design of the FUN (France Université Numérique) data processing chain

Étude des méthodes IA d'analyse de données (machine learning / deep learning) pour l'amélioration du contenu des MOOCs informatiques et contribution à la conception de la chaîne de traitement des données de FUN (France Université Numérique) Les cours en ligne ouverts et massifs (MOOC), introduits en 2008 et popularisés par des ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Editorial: Integration of advanced technologies in orchard management. [PDF]

Front Plant Sci
da Vitoria EL, Yu Z.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Multi-Head Attention Transformer Model for Wearable in Situ Fall Detection. [PDF]

IEEE Access
Tian J, Xu S, Gerstoft P, Sarkar M, Moore AA, Mercier P, Paolini C.   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source