Results 211 to 220 of about 24,210,199 (329)

A case report of non-lamin A/C dilated cardiomyopathy presenting in a patient with Najjar-Malouf syndrome. [PDF]

Eur Heart J Case Rep
Flury G, Arquint F.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Orthopaedic portrayals in The Seven Works of Mercy painted by a Dutch master in the year 1504. [PDF]

Int Orthop
Bult SA, de Ruiter PEJ, Vergroesen PA, van Gulik TM.   +3 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Lonergan on Imitating the Divine Relations [PDF]

, 2013
Doran, Robert M.
core   +1 more source

Prognostic significance and regulatory role of ACOT7 in the tumor immune microenvironment of breast invasive ductal carcinoma: a multi-omics analysis. [PDF]

Front Immunol
Song C, Quan Y, Shan Y, Chen Y, Du J, Li K, Li N.   +6 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Linked color imaging improves polyp miss rates in total colonoscopy in a multicenter randomized back to back trial. [PDF]

Sci Rep
Shimoda R, Yamaguchi D, Hashiguchi K, Mizukami K, Aso A, Akutagawa T, Miyahara K, Honda T, Hashiguchi K, Ohira T, Fukuda K, Kabayama M, Miyamoto H, Gushima R, Sumida Y, Suzuki S, Sasaki F, Yamaguchi N, Kinjo T, Miike T, Ohnita K, Moriyama T, Fujioka S, Shono T, Shirai S, Ohtsu K, Kiyomi F.   +26 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

GDF10 attenuates MASH progression by restoring quiescent hepatic stellate cells via competitive inhibition of TGF-β/SMAD2 signaling. [PDF]

Int J Biol Sci
Peng Y, Lei H, Zhao J, Wang H, Luo Z, Wang D, Shi S, Wang T, Li J, Pang Z, Wang B, Xiong X.   +11 more
europepmc   +1 more source