Results 141 to 150 of about 28,117,703 (382)
Normative Models for the Protection of Children and Teenagers’ Personal Data [PDF]
Hugo Damasceno Teles +1 more
openalex
Social Protection Index Brief: Social Assistance Programs in Asia and the Pacific [PDF]
[Excerpt] The Asian Development Bank (ADB) report The Social Protection Index: Assessing Results for Asia and the Pacific (2013) documents the role of social assistance in social protection systems across the region.
Handayani, Sri W, McKinley, Terry
core +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Practical, legal, and ethical reasons necessitate the development of methods to replace animal experiments. Computational techniques to acquire information that traditionally relied on animal testing are considered a crucial pillar among these so-called ...
Jochen P. Zubrod +3 more
doaj +1 more source
European Court of Human Rights : Satakunnan Markkinapörssi Oy and Satamedia Oy v. Finland [PDF]
The Grand Chamber judgment of European Court of Human Rights (ECtHR) finds that a prohibition issued by the Finnish Data Protection Board that prohibited two media companies from publishing personal taxation data in the manner and to the extent they had ...
Voorhoof, Dirk
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Lightweight Network for Corn Leaf Disease Identification Based on Improved YOLO v8s
This research tackles the intricate challenges of detecting densely distributed maize leaf diseases and the constraints inherent in YOLO-based detection algorithms.
Rujia Li +8 more
doaj +1 more source

