Results 191 to 200 of about 1,028,701 (293)

Modelling the health, financial protection and equity impacts of upscaling the ACT NOW early intervention breast cancer pilot program in the Philippines: an extended cost-effectiveness analysis. [PDF]

BMJ Glob Health
Chye A, Jan S, Pathy NB, Luna HGC, Lim SB, Kimman M, Woodward M, Peters S, Monaghan H, Ngelangel CA, Angell B.   +10 more
europepmc   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Role of Gender Equity and Disability Inclusion to Help Achieve the Larger Cause of Health for All and Attain SDG 2030 by India. [PDF]

Indian J Community Med
Kar S, Bashar A, Gnanasekaran S, Jayasree AK, Indu PS, Srivastava K.   +5 more
europepmc   +1 more source

Inhibition of the clathrin terminal domain – amphiphysin protein‐protein interaction. Probing the Pitstop® 2 aromatic moiety.

ChemMedChem, Accepted Article.
Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)‐4‐oxo‐4,5‐dihydrothiazol‐2‐yl)naphthalene‐1‐sulfonamide (1), inhibits the clathrin terminal domain‐ amphiphysin interaction (NTD‐PPI) and has been widely used to investigate endocytosis. In this work we report on the synthesis of 56 novel Pitstop 2 analogues via four discrete focused libraries.
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

Growing old before growing rich: a scoping review on ageing-related policy interventions from the WHO Southeast Asian Region. [PDF]

BMJ Open
Mohan A, Jaihind Jothikaran TA, Gudi N, A K A, Ashok L.   +4 more
europepmc   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, Accepted Article.
Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Rumination Time, Reticulorumen Temperature, and Activity in Relation to Postpartum Health Status in Dairy Cows During Heat Stress. [PDF]

Animals (Basel)
Szalai S, Bodnár Á, Fébel H, Bakony M, Jurkovich V.   +4 more
europepmc   +1 more source

Can and should misappropriation also protect databases? A comparative approach [PDF]

, 2007
Derclaye, Estelle
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