Results 71 to 80 of about 192,753 (304)

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

Blockchain-Based Solution for the Traceability of Spare Parts in Manufacturing

open access: yesIEEE Access, 2020
Spare parts are essential assets to maintain productivity and operations. A spare part is used for the repair or replacement of failed units. Tracing and tracking of spare parts ownership can help to ensure reliable outcomes in terms of manufacturing ...
Haya R. Hasan   +5 more
doaj   +1 more source

Modelling the Provenance of Data in Autonomous Systems

open access: yes, 2007
Determining the provenance of data, i.e. the process that led to that data, is vital in many disciplines. For example, in science, the process that produced a given result must be demonstrably rigorous for the result to be deemed reliable.
Luck, Michael   +11 more
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

Requirements for Provenance on the Web [PDF]

open access: yes, 2012
From where did this tweet originate? Was this quote from the New York Times modified? Daily, we rely on data from the Web, but often it is difficult or impossible to determine where it came from or how it was produced.
Cheney, J   +13 more
core   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Extended access control mechanism for cross-domain data exchange

open access: yesTongxin xuebao, 2019
Aiming at the controlled sharing for cross-domain data exchange for complicated application systems,an extended access control mechanism was proposed.The control process was divided into two steps:constraint control and propagation control.The constraint
Rongna XIE   +5 more
doaj  

Transchain: Blockchain-Based Management of Allografts for Enhancing Data Provenance

open access: yesIEEE Access
Recent technological advances have enabled researchers to investigate various novel approaches utilized to manage allograft transplants and overcome the challenges of conventional centralized systems.
Rashid Ul Haq   +5 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

open access: yesAdvanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou   +10 more
wiley   +1 more source

Data Foundations for Medical AI: Provenance, Reliability and Limitations of Russian Clinical NLP Resources

open access: yesInformatics
Russian-language resources for medical natural language processing (NLP) are expanding rapidly; however, their fragmentation, uneven curation, and limited clinical reliability hinder the development of safe machine learning systems for prognosis ...
Arsenii Litvinov   +8 more
doaj   +1 more source

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