Results 131 to 140 of about 4,335,424 (343)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The Research Data Management Workbook: Building a Collection of Data Management Exercises to Bridge Data Information Literacy and Data Management Implementation

open access: yesJournal of eScience Librarianship
Objective: There are limited opportunities and resources for data information literacy at small universities, requiring instructors to make the most of the time they have in the classroom.
Kristin Briney
doaj   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Data publishing while preserving data privacy

open access: yes, 2014
Over the last decade, the Data Science team at Harvard's Institute for Quantitative Social Science has been iteratively developing Dataverse, a data repository framework to facilitate and enhance research transparency through data sharing, preservation, citation, reuse and analysis.
openaire   +1 more source

Data publishing and archival

open access: yes, 2021
Slides used for the Data publishing and archival session of training on "Best practices and Data Management and Stewardship" held by ELIXIR Luxembourg on 17 June 2021.
openaire   +1 more source

FPDP: Flexible Privacy-Preserving Data Publishing Scheme for Smart Agriculture

open access: green, 2020
Jingcheng Song   +5 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Research data openness:development,models and new exploration

open access: yes大数据, 2016
The concept and clarification of research data were analyzed.Judging from the aspects of principals,policies,technologies and procedures,the current state of research data openness was described.The practices have been summarized into three main kinds ...
HANG Z, LI Lili,
doaj  

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