Results 161 to 170 of about 34,637,647 (310)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2009 Vincent S. Smith, Data publication: towards a database of everything, BMC Research Notes, June 24, 2009.
openaire +1 more source
Railway, postal & telegraph map of Queensland 1888 [cartographic material] /
, 1888 Map of Queensland showing railways, places with postal and telegraph services and average annual rainfall. Has index to towns.; Folded map from Vol. 2 of: Picturesque Atlas of Australasia. Sydney : Picturesque Atlas Publishing Company, Limited, 1886-1889.
Picturesque Atlas Publishing Company.
core
Privacy preserving data publishing of categorical data through k-anonymity and feature selection. [PDF]
Healthc Technol Lett, 2016 Aristodimou A +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The data paper: a mechanism to incentivize data publishing in biodiversity science. [PDF]
BMC Bioinformatics, 2011 Chavan V, Penev L.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
This presentation on Data Sharing & Publishing was created for a joint online workshop held by Ludwig Maximilian University of Munich and ZB MED – Information Centre for Life Sciences on 7 May 2024.
Gabriel, Vanessa +3 more
openaire +2 more sources