Results 231 to 240 of about 4,194,830 (297)
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Cell Death Disease turns 15: legacy of service, horizon of challenges. [PDF]
Melino G, Shi Y, Simon HU, Piacentini M.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Ethical Challenges in Scientific Publishing: Insights from New Fireside Chats at the 2025 European Society of Cardiology Congress. [PDF]
Mugelli A.
europepmc +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
An open letter to the NIH: value and costs in publishing. [PDF]
Jackson S +6 more
europepmc +1 more source
Scratchpads: a data-publishing framework to build, share and manage information on the diversity of life. [PDF]
Smith VS +4 more
europepmc +1 more source
A new look GigaDB. Data publishing gets more interactive and FAIR.
Mary Ann Tuli
openalex +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source

