Results 51 to 60 of about 22,562,908 (328)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Privacy-Preserving Social Media Data Publishing for Personalized Ranking-Based Recommendation
IEEE Transactions on Knowledge and Data Engineering, 2019 Personalized recommendation is crucial to help users find pertinent information. It often relies on a large collection of user data, in particular users’ online activity (e.g., tagging/rating/checking-in) on social media, to mine user preference. However,
Dingqi Yang +2 more
semanticscholar +1 more source
Enhanced Publications: Data Models and Information Systems
Liber Quarterly: The Journal of European Research Libraries, 2014 “Enhanced publications” are commonly intended as digital publications that consist of a mandatory narrative part (the description of the research conducted) plus related “parts”, such as datasets, other publications, images, tables, workflows, devices ...
Alessia Bardi, Paolo Manghi
doaj +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
A Model-based Chatbot Generation Approach to Converse with Open Data Sources [PDF]
, 2020 The Open Data movement promotes the free distribution of data. More and more companies and governmental organizations are making their data available online following the Open Data philosophy, resulting in a growing market of technologies and services to help publish and consume data. One of the emergent ways to publish such data is via Web APIs, which
arxiv +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Analysis of Determinations of the Distance between the Sun and the Galactic Center [PDF]
Astronomy Reports, 2013, v. 57, No. 2, pp. 128-133, 2013 The paper investigates the question of whether or not determinations of the distance between the Sun and the Galactic center R0 are affected by the so-called "bandwagon effect", leading to selection effects in published data that tend to be close to expected values, as was suggested by some authors.
arxiv +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Publishing NextGEOSS data on the GEOSS Platform
Big Earth Data, 2023 This paper is the second of a series that describes some of the main dataset resources presently shared through the GEOSS Platform. The GEOSS Platform was created as the technological tool to implement interoperability among the Global Earth Observation ...
Roberto Roncella +6 more
doaj +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source