Results 241 to 250 of about 32,662,171 (307)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A framework for identifying cost efficiencies in malaria routine data quality audits: methodology and application in Zambia. [PDF]

Malar J
Nguyen A, Malama P, Lungu C, Mwanza M, Phiri D, Silumbe K, Chiwaula J, Hainsworth M, Das S, Roca-Feltrer A.   +9 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Increasing X-ray energy improves data quality in serial crystallography. [PDF]

J Synchrotron Radiat
Gu DH, Axford D, Beilsten-Edmands J, Jaho S, Owen RL.   +4 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Immunization data management practices and data quality in Ethiopia. [PDF]

Arch Public Health
Daka DW, Yeheyis T, Amare G, Kiflie Y, Abera A, Gutema K, Taye G, Fikadie B, Birhanu Z, Dheressa M, Biyana CF, Alemu K, Abera N, Wordofa MA, Ayanaw Y, Berhanu A, Tamiso A, Kifle A, Tilahun B, Wondirad Y, Awel T, Mengesha M, Mohammed M, Wondirad N, Lakew Y, Zelalem M, Ayalew M, Solomon S, Hawulte B.   +28 more
europepmc   +1 more source

Factors influencing data quality in electronic health records among health professionals in hospital settings: a scoping review protocol. [PDF]

BMJ Open
Brinkmann EM, Haahr A, Bossen C, Aadal L.   +3 more
europepmc   +1 more source

Landscape analysis towards data quality and utility labelling in the European Health Data Space. [PDF]

Eur J Public Health
Sánchez-García Á, Proietti Mercuri C, Schutte N, Estupiñán-Romero F, Tellería-Orriols C, Doñate-Martínez A, García-Gómez JM, Bernal-Delgado E, Sáez C, On Behalf Of Quantum.   +9 more
europepmc   +1 more source

An audit assessing data quality, viral suppression, and transition to dolutegravir among children and adolescents with HIV in care at eThekwini Municipality, South Africa

Hlabisa M, Mtila L, Lushaba N, Tlhaku K, Archary M, van der Molen JS, Mbeje S, Khubone T, Luthuli N, Mahomed S, Garrett N, Lewis L, Dorward J, Sookrajh Y, Brown JA.   +14 more
europepmc   +1 more source

Quantifying the Impact of Anonymization-Induced Clinical Data Quality Loss: Methodological Quantitative Case Study Using Primary Diagnosis Codes and Hospital Length of Stay. [PDF]

JMIR Med Inform
Kamdje Wabo G, Sokolowski PP, Jannesari Ladani M, Hagmann M, Ganslandt T, Siegel F.   +5 more
europepmc   +1 more source