Results 181 to 190 of about 3,597,090 (249)

Retraction Note: Management of uterine leiomyoma and adenomyosis: role of hysteroscopy in diagnosis and norethindrone in the treatment. [PDF]

Sci Rep
Ali A, Youssef A, El Saman A, Taleb HA.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Enhancing antimicrobial resistance (AMR) surveillance data use in Uganda. [PDF]

Antimicrob Steward Healthc Epidemiol
Chukwuma U, Mayito J, Twemanye V, Namusoosa R, Kakyakumaiso D, Otita M, Tabajjwa D, Guma C, David Brett-Major D, Walmema R.   +9 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Development and Assessment of a Pipeline for Extracting Structured Data From Free-Text Medical Reports Using a Large Language Model. [PDF]

JCO Clin Cancer Inform
Joseph E, Vallee P, Perennec T, Wagneur N, Frenel JS, Campone M, Bocquet F, Le Borgne F.   +7 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Quality of life in oncology drug approvals: evidence from Swiss decisions in relation to global regulatory trends. [PDF]

Qual Life Res
Horst A, Löffler-Perez N, Rohr UP, Wac K.   +3 more
europepmc   +1 more source

Data management Report

This report summarises the data management activities of the project. It will include details on which data was handled inside the project, how it is protected and stored and which data is made publicly available.
openaire   +1 more source