Results 251 to 260 of about 3,453,488 (306)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A repeated awakening study exploring the capacity of complexity measures to capture dreaming during propofol sedation. [PDF]

Sci Rep
Bajwa IJ, Nilsen AS, Skukies R, Aamodt A, Ernst G, Storm JF, Juel BE.   +6 more
europepmc   +1 more source

Global safety profile of PD-1/PD-L1 inhibitors in hepatic autoimmune disorders: A global disproportionality analysis. [PDF]

Medicine (Baltimore)
Oh J, Kong J, Hwang J, Kim TH, Park J, Cho J, Kim TH, Yon DK.   +7 more
europepmc   +1 more source

Large language models for extracting histopathologic diagnoses of colorectal cancer and dysplasia from electronic health records. [PDF]

BMJ Open Gastroenterol
Johnson B, Bath T, Huang X, Lamm M, Earles A, Eddington H, Dornisch AM, VA Million Veteran Program, Jih LJ, Gupta S, Shah SC, Curtius K.   +11 more
europepmc   +1 more source

Real-World Safety Concerns of Tirzepatide: A Retrospective Analysis of FAERS Data (2022-2025). [PDF]

Healthcare (Basel)
Almansour HA, Thaibah HA, Alfarhan M, Al-Qahtani SA, Khardali AA, Alshammari TM.   +5 more
europepmc   +1 more source

Inflammation and mutational burden differentially associated with nivolumab or ipilimumab combination efficacy in colorectal cancer. [PDF]

Nat Commun
Lei M, Overman MJ, Yao J, André T, Lonardi S, Lenz HJ, Aglietta M, Gelsomino F, McDermott R, Wong KYM, Morse MA, Van Cutsem E, Hendlisz A, Cardin DB, Neyns B, Hill A, Krishnamurthy A, Chen F, Kochuparambil S, Jenq RR, Abdullaev S, He B, Novosiadly R, Kopetz S.   +23 more
europepmc   +1 more source

[Retracted] Expression of α‑fetoprotein in gastric cancer AGS cells contributes to invasion and metastasis by influencing anoikis sensitivity. [PDF]

Oncol Rep
Lu S, Ma Y, Sun T, Ren R, Zhang X, Ma W.
europepmc   +1 more source

Leveraging GPT-4o for Automated Extraction and Categorization of CAD-RADS Features From Free-Text Coronary CT Angiography Reports: Diagnostic Study.

JMIR Med Inform
Chen Y, Dong M, Sun J, Meng Z, Yang Y, Muhetaier A, Li C, Qin J.   +7 more
europepmc   +1 more source

Building a Standardized Cancer Synoptic Report With Semantic and Syntactic Interoperability: Development Study Using SNOMED CT and Fast Healthcare Interoperability Resources (FHIR).

JMIR Med Inform
Hwang J, Goel AK, Rous BA, Birdsong G, Seegers PA, Dubois S, Rüdiger T, Campbell WS.   +7 more
europepmc   +1 more source

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To Report or Not Report Health Care Data Breaches

The American Journal of Managed Care, 2020
The study's objectives were to explore the impact of personal/organizational knowledge, prior breach status of organizations, and framed scenarios on the choices made by privacy officers regarding the decision to report a breach.A survey was completed of 123 privacy officers who are members of the American Health Information Management Association ...
Kendall Cortelyou-Ward, Meghan Hufstader Gabriel, Amanda Walden, Alice Noblin   +3 more
openaire   +3 more sources