Results 61 to 70 of about 3,597,090 (249)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
STUDY REGARDING THE EVOLUTION OF THE WAY IN WHICH DATA ANALYSIS SOFTWARE TOOLS ARE USED IN MARKETING ACTIVITY BY THE WESTERN ROMANIAN COMPANIES [PDF]
Annals of the University of Oradea: Economic Science, 2016 Marketing activities involve the use of large amounts of information. In order to be used effectively in decision making, they must be processed, presented in a form suitable and properly analyzed.
Naiana Ţarcă, Adela Popa
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Excel Data Mining Add-in. Applications in audit and financial reports
Audit Financiar, 2017 Performance reasons in decision making based on business data usually requires a good management of multiple data formats and also processing speed, flexibility, portability, automation, power of suggestion and ease of use.
Dinu AIRINEI, Daniel HOMOCIANU
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Data-driven clinical improvement: Oncology nurse leaders' perceptions and experiences of organisational data reports. [PDF]
J Nurs Manag, 2022 Mazzella-Ebstein AM +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
GeoresursyThe article describes the project being developed for the digital scientific platform “Aggregator of unstructured geological and field data”, which could potentially be important for the oil and gas industry.
O. A. Nevzorova +2 more
doaj +1 more source
Moving beyond annual data reports: A blueprint for communicating and disseminating actionable intelligence. [PDF]
J Clin Transl Sci, 2022 Ruiz R +5 more
europepmc +1 more source