Results 91 to 100 of about 24,619,351 (316)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Scientific Data Repositories: Aspects About Data Privacy [PDF]
, 2017 Artigo apresentado no I Workshop de Informação, Dados e Tecnologia, realizado entre nos dias 04 e 06 de setembro de 2017, na cidade de Florianópolis (SC), no Auditório do Espaço Físico Integrado (EFI) da Universidade Federal de Santa Catarina (UFSC ...
Affonso, Elaine Parra +3 more
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
eLifeAs a heterogenous disease with likely multiple pathogeneses and as-yet-undefined subtypes, progress in endometriosis treatment is currently limited by a lack of appropriate models and cohorts for research.
Kate Gunther +4 more
doaj +1 more source
Remote Sensing, 2016 Marine processes are observed with sensors from both the ground and space over large spatio-temporal scales. Citizen-based contributions can fill observational gaps and increase environmental stewardship amongst the public.
Julia A. Busch +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Raising the visibility of protected data: A pilot data catalog project [PDF]
, 2020 Sharing research data that is protected for legal, regulatory, or contractual reasons can be challenging and current mechanisms for doing so may act as barriers to researchers and discourage data sharing.
Coates, Heather L., Foster, Erin D.
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Imbalanced target prediction with pattern discovery on clinical data repositories
BMC Medical Informatics and Decision Making, 2017 BackgroundClinical data repositories (CDR) have great potential to improve outcome prediction and risk modeling. However, most clinical studies require careful study design, dedicated data collection efforts, and sophisticated modeling techniques before ...
Tak-Ming Chan +5 more
semanticscholar +1 more source
Classifying document types to enhance search and recommendations in digital libraries
, 2017 In this paper, we address the problem of classifying documents available from the global network of (open access) repositories according to their type. We show that the metadata provided by repositories enabling us to distinguish research papers, thesis ...
F Sebastiani +2 more
core +1 more source