Results 101 to 110 of about 846,245 (303)

Recent Advances in Satellite Data Rescue

Bulletin of the American Meteorological Society, 2017
Abstract To better understand the impacts of climate change, environmental monitoring capabilities must be enhanced by deploying additional and more accurate satellite- and ground-based (including in situ) sensors. In addition, reanalysis of observations collected decades ago but long forgotten can unlock precious information about the ...
Dick P. Dee, Paul Poli, Roger Saunders, Viju O. John, Peter Rayer, Jörg Schulz, Kenneth Holmlund, Dorothee Coppens, Dieter Klaes, James E. Johnson, Asghar E. Esfandiari, Irina V. Gerasimov, Emily B. Zamkoff, Atheer F. Al-Jazrawi, David Santek, Mirko Albani, Pascal Brunel, Karsten Fennig, Marc Schröder, Shinya Kobayashi, Dieter Oertel, Wolfgang Döhler, Dietrich Spänkuch, Stephan Bojinski   +23 more
openaire   +2 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

SMaSH: A Benchmarking Toolkit for Human Genome Variant Calling

, 2014
Motivation: Computational methods are essential to extract actionable information from raw sequencing data, and to thus fulfill the promise of next-generation sequencing technology. Unfortunately, computational tools developed to call variants from human
Bresler, Ma'ayan, Curtis, Kristal, Hartl, Christopher, Jordan, Michael I., Liptrap, Jesse, Newcomb, Julie, Patterson, David, Song, Yun S., Talwalkar, Ameet, Terhorst, Jonathan   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Meteorological data rescue: Citizen science lessons learned from Southern Weather Discovery. [PDF]

Patterns (N Y), 2022
Lorrey AM, Pearce PR, Allan R, Wilkinson C, Woolley JM, Judd E, Mackay S, Rawhat S, Slivinski L, Wilkinson S, Hawkins E, Quesnel P, Compo GP.   +12 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Southern Ocean sea ice, icebergs, and meteorological data from maritime sources for the period 1929 to 1940

Geoscience Data Journal
Maritime historical documentary sources of weather and state of sea surface including sea ice can aid in filling a known climate knowledge gap for the Southern Ocean and Antarctica for the first half of the 20th century. This study presents a data set of
Dmitry V. Divine, Svetlana Divina, Ole Edvard Bjørge, Elisabeth Isaksson, Harald Dag Jølle, Ivar Stokkeland, Mariela Vasquez Guzman, Sally Wilkinson, Clive Wilkinson   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source