Results 111 to 120 of about 846,245 (303)
Risky Business: Data-At-Risk in a Dynamic and Evolving Multidisciplinary Research Environment
Data Science JournalAt-risk data is an unfortunate research reality and can be present in all data formats in a range of research disciplines. This is defined as data that are at risk of loss due to various factors, including deterioration of the media, lack of accompanying
Louise H. Patterton +2 more
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Design of mine rescue robot group
Gong-kuang zidonghua, 2019 In view of problems of poor adaptability, communication ability and maneuverability of current mine robots, a mine rescue robot group was designed. The robot group mainly includes a communication robot, a search and rescue robot, an auxiliary rescue ...
WEN Hu, LIU Yang, ZHENG Xuezhao, GUO Jun
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Research on rescue priority based on high spatiotemporal resolution mobile positioning data
Natural Hazards ResearchEstimate the key rescue areas of earthquake accurately, which is of great significance for deploying rescue forces and implementing rescue activities in post-earthquake scientifically.This paper based on the idea of first zoning, then classification, and
Na Gao, Jingjing Liu, Lijuan Yuan
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Geoscience Data JournalWe describe the transcription and quality control processes for rescuing around 570,000 sub‐daily and daily weather observations which were recorded in the UK Met Office Daily Weather Reports during the 1861–1875 period.
Philip M. Craig, Ed Hawkins
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Frontiers in Public HealthIntroductionThe evaluation of the accessibility of prehospital emergency medical facilities plays a vital role in the rational allocation of urban medical resources.
Feng Tian +13 more
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AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source