Results 61 to 70 of about 958,621 (305)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Business Retention and Expansion Aggregated Data
These data were collected in individual business surveys over the past 25 years as part of the Extension's Center for Community Vitality Business Retention and Expansion (BRE) program, and have been aggregated to the community level for release.
University of Minnesota Extension Center for Community Vitality, Business Retention and Expansion Program
core +1 more source
La sentenza 𝑡𝑒𝑙𝑒2 𝑆𝑣𝑒𝑟𝑖𝑔𝑒: verso una 𝑑𝑖𝑔𝑖𝑡𝑎𝑙 𝑟𝑢𝑙𝑒 𝑜𝑓 𝑙𝑎𝑤 europea? [PDF]
IANUS Diritto e Finanza, 2017 Nel dicembre 2016 la Corte di Giustizia dell’Unione Europea si è pronunciata sul ricorso Tele2 Sverige, l’ultimo atto di lunga querelle in tema di data retention.
Elisa Spiller
doaj
Intron Retention as a Mode for RNA-Seq Data Analysis
Frontiers in Genetics, 2020 Intron retention (IR) is an alternative splicing mode whereby introns, rather than being spliced out as usual, are retained in mature mRNAs. It was previously considered a consequence of mis-splicing and received very limited attention. Only recently has
Jian-Tao Zheng +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Assessing User Retention of a Mobile App: Survival Analysis
JMIR mHealth and uHealth, 2020 BackgroundA mobile app generates passive data, such as GPS data traces, without any direct involvement from the user. These passive data have transformed the manner of traditional assessments that require active participation from the user.
Lin, Yu-Hsuan +6 more
doaj +1 more source
Research data retention and disposal process and metadata requirements
, 2022 Curtin University is a participating institution of the ARDC Institutional Underpinnings Program (2021-22). Curtin’s implementation project aimed at developing a process to manage research data retention and disposal based on recommendations set out in ...
Chan, Janice, Jeffery, Dianne
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
How could primary care meet the informatics needs of UK Biobank? A Scottish proposal
Journal of Innovation in Health Informatics, 2003 UK Biobank is an ambitious post-genomic project involving the recruitment and follow-up of 500 000 volunteers aged 45 to 69 years. Many primary care teams will be involved in the study directly or indirectly.
Frank Sullivan +3 more
doaj +1 more source