Results 221 to 230 of about 53,144,553 (313)

Fringe Benefits Survey, 1992

The survey deals with fringe benefits in working life, the objective was to map out the extent and distrubution of this type of benefits. The need for the survey was identified by a registration of a one-sided focus on monetary payments in other surveys ...
Norwegian Social Science Data Services
core  

The Big Data Science Center at the Shanghai Synchrotron Radiation Facility: the architecture of the superfacility. [PDF]

J Synchrotron Radiat
Li X, Wang C, Chen J, Wan R, Ye J, Li Q, Cai H, Zhang Y, Li A, Tai R, Sepe A.   +10 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Data science without borders: bridging the divide in data science capacity across African health institutions. [PDF]

Front Public Health
Kiragga AN, Iddi S, Walekhwa AW, Barasa M, Cygu S, Odhiambo R, Gningue M, Mboup A, Onana A, Adnew B, Alemu Ashuro A, Hudson S, Greenfield J, Todd J, Bhattacharjee T, Sharan M, Sonabend R, Kadengye D, Mbatchou BH, Abdissa A, Sarr M, Nabende JN, Bamutura M, Tamurat B, Dereje N, Temfack E.   +25 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Unleashing potential: assessing Africa's readiness for the data science revolution to impact health. [PDF]

Nat Commun
Panji S, Ras V, Gichoya J, Julius R, Maslamoney S, Motshegwa T, Sharaf A, Skelton M, Tunga M, Mulder N.   +9 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A strategic framework for data science integration in undergraduate medical education and clinical training. [PDF]

J Educ Health Promot
Narasimhaswamy N, Bhat S, Nagaraj A, Sori RK, Ganesan S, Poojar B.   +5 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

1. Data Science [PDF]

Digitale Welt, 2018
openaire   +1 more source