Results 251 to 260 of about 13,470,212 (338)

Eleven quick tips to unlock the power of in vivo data science. [PDF]

PLoS Comput Biol
Kieran TJ, Maines TR, Belser JA.
europepmc   +1 more source

Replication data for: The Political Economy of IMF Lending in Africa. American Political Science Review, 2004

, 2007
Randall W. Stone
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Ethical governance for genomic data science in the cloud. [PDF]

Nat Rev Genet
Rahimzadeh V, Nelson SC, Thorogood A, Lawson J, Fullerton SM.   +4 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Leveraging data science to understand and address multimorbidity in sub-Saharan Africa: the MADIVA protocol. [PDF]

BMJ Health Care Inform
Glover K, Osler T, Adetunji K, Akumu T, Asiki G, Awuor D, Boua P, Bronstein V, Byamugisha J, Du Toit JD, Dwolatzky B, George J, Harris PA, Herbst K, Hofman K, Holden C, Iddi S, Kadengye DT, Kahn K, Kamp M, Khoza N, Kimongo F, Kisiangani I, Kogda DE, Klipin M, Levitt SP, Maghini D, Maila K, Maimela E, Nderitu DM, Makondo N, Maoyi ML, Mashaba RG, Masilela NG, Mathema T, Mpangase PT, Nyachowe DT, Ohene-Kwofie D, Robertson H, Speakman S, Thsehla E, Thwala SA, Zent R, Gómez-Olivé FX, Kabudula CW, Owili PO, Kyobutungi C, Ramsay M, Tollman S, Hazelhurst S.   +49 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Augmenting Circadian Biology Research With Data Science. [PDF]

J Biol Rhythms
Soltani S, Burks JH, Smarr BL.
europepmc   +1 more source

Relational Strategies for Processing Universally Quantified Queries to Large Data Bases (Mathematical Methods in Software Science and Engineering)

, 1979
Koichi Furukawa
openalex   +1 more source