Results 261 to 270 of about 12,937,092 (315)

Semantic hyperspectral image synthesis for cross-modality knowledge transfer in surgical data science. [PDF]

Int J Comput Assist Radiol Surg
Tran Ba V, Hübner M, Bin Qasim A, Rees M, Sellner J, Seidlitz S, Christodoulou E, Özdemir B, Studier-Fischer A, Nickel F, Ayala L, Maier-Hein L.   +11 more
europepmc   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

The ImageGuideEcho Registry: Using Data Science to Understand and Improve Echocardiography. [PDF]

Curr Cardiol Rep
Spetko N, Oribabor J, Anyanwu E, Tyler TBI, Rodriguez DF, Ouyang D, Strom JB.   +6 more
europepmc   +1 more source

The INTEGRAL Science Data Centre

, 2002
V. Beckmann
openalex   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Bridging the gap: enhancing data science and leadership knowledge and skills in the context of the public health workforce. [PDF]

Front Public Health
Hamer D, Gustafson M, Gumina CO, Landis DC, Bockelman P, Perry E, Matthews SD.   +6 more
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Balancing ethical data sharing and open science for reproducible research in biomedical data science. [PDF]

Cell Rep Med
Lvovs D, Creason AL, Levine SS, Noble M, Mahurkar A, White O, Fertig EJ.   +6 more
europepmc   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Growing Data science Research in Africa to Stimulate Progress (GRASP) program: Rationale and overview. [PDF]

Equity Neurosci
Uvere E, Kumuthini J, Fatumo S, Taiwo J, Akinyemi R, Ogunniyi A, Ogbole G, Aribisala B, Sarfo F, Jegede A, Akinyemi J, Vedanthan R, Okekunle A, Lackland D, Ovbiagele B, Owolabi M.   +15 more
europepmc   +1 more source