Results 61 to 70 of about 1,685,768 (265)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Difficulties in the collection of data and information in Romania

Annals of Spiru Haret University Economic Series, 2011
The purpose of this paper is to highlight the difficulties encountered by any person or company when searching for valuable information on the official sites of the ministries or state institutions, using the available search keys.
Elisabeta Haba, Sabina Popescu, Victor Velter   +2 more
doaj  

Pemanfaatan Algoritma Sequential Search Dalam Penerapan Aplikasi Inventaris

Journal of Electrical Engineering and Computer
Inventaris di SMA XYZ mengalami ketidakefisienan karena melibatkan entri data satu per satu secara manual ke dalam buku inventaris. Hal ini mengakibatkan kesulitan yang berkelanjutan dalam memproses data inventaris, terutama dalam menyajikan informasi ...
Sandhy Fernandez, AR Walad Mahfuzhi, Baharudin Rabbani   +2 more
doaj   +1 more source

MetaQA: Enhancing human-centered data search using Generative Pre-trained Transformer (GPT) language model and artificial intelligence. [PDF]

PLoS One, 2023
Li D, Zhang Z.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Data provision for IoT searches:an auction approach

Tongxin xuebao, 2015
Getting accurate data was one of keys problems in the IoTs search.Different from the Web searches that use the crawlers to collect data on the Internet,the IoT searches require that owners offer data proactively because their data were not simply ...
Li-hua YIN, Yun-chuan GUO, Hui-bing ZHANG   +2 more
doaj   +2 more sources

Data security and protection techniques in big data:a survey

网络与信息安全学报, 2016
Big Data has attracted tremendous attention from all over the world nowadays.Its sheer volume,complex structure and realtime processing requirements often obsolete traditional technologies when coming to provide suffi-cient security protection.To address
Kai-min WEI,Jian WENG, Kui REN
doaj   +1 more source

Application of big data search based on collaborative filtering algorithm in cross-border e-commerce product recommendation. [PDF]

Soft comput, 2023
Wu X, Wu Z.
europepmc   +1 more source

Searches as data: archiving and sharing search strategies using an institutional data repository

Journal of the Medical Library Association
Background: By defining search strategies and related database exports as code/scripts and data, librarians and information professionals can expand the mandate of research data management (RDM) infrastructure to include this work. This new initiative aimed to create a space in McGill University’s institutional data repository for our librarians to ...
Alisa Rod, Jill Boruff
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source