Results 21 to 30 of about 3,165,354 (231)

Designing privacy for scalable electronic healthcare linkage [PDF]

open access: yes, 2009
A unified electronic health record (EHR) has potentially immeasurable benefits to society, and the current healthcare industry drive to create a single EHR reflects this.
Ajayi, O.   +3 more
core   +2 more sources

Detecting periodic subsequences in cyber security data

open access: yes, 2017
Statistical approaches to cyber-security involve building realistic probability models of computer network data. In a data pre-processing phase, separating automated events from those caused by human activity should improve statistical model building and
Heard, Nick   +2 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Strengthening Data Security: an Holistic Approach [PDF]

open access: yes, 2008
In the light of heightened concern around data security, this paper highlights some of the measures that can be used to develop and strengthen security in data archiving. The paper includes discussion of the different approaches that can be taken towards
Bolton, S, Woollard, M
core  

Some Potential Issues with the Security of HTML5 IndexedDB [PDF]

open access: yes, 2014
The new HTML5 standard provides much more access to client resources, such as user location and local data storage. Unfortunately, this greater access may create new security risks that potentially can yield new threats to user privacy and web attacks ...
Ellman, Jeremy   +2 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Survey of Physical Layer Security Techniques for 5G Wireless Networks and Challenges Ahead [PDF]

open access: yes, 2018
Physical layer security which safeguards data confidentiality based on the information-theoretic approaches has received significant research interest recently.
Caire, Giuseppe   +5 more
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

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