Results 161 to 170 of about 3,643,121 (304)

Data Sharing Advances Rare and Neglected Disease Clinical Research and Treatments

, 2019
Rachelle J. Bienstock
openalex   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Open science: My insights into data sharing, preregistration, and replication. [PDF]

Can J Exp Psychol
Hart SA.
europepmc   +1 more source

Common Data Format for Program Sharing and Integration [PDF]

, 2003
E. Rossi, Andrew Emerson, Stefano Evangelisti   +2 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Blockchain Technology for Big-data Sharing in Material Genome Engineering. [PDF]

Sci Data
Wang R, Ye F, Tang S, Zhang H, He J, Zhang X, Xu C.   +6 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Data sharing practices and experiences among Alzheimer's disease and related dementia researchers. [PDF]

Alzheimers Dement
Arias JJ, Nielsen KE, Bolcic-Jankovic D, Bonham LW, Campbell EG, Lah JJ, Manchester MA, Scipion CEA, Wang Y, Wolf LE, Mello MM, Yokoyama JS.   +11 more
europepmc   +1 more source

Development of an application to anonymize data to be shared in the cloud

, 2022
David González Marrón, Verónica Paola Corona Ramírez, Angélica Enciso González, Alejandro Márquez Callejas, Iridian Sandivel Pérez Hernández   +4 more
openalex   +1 more source