Results 51 to 60 of about 128,909 (307)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A laser-equipped chamber for the assessment of sprint swimming traits in fishes
Frontiers in Ecology and EvolutionSprint swimming performance in fishes is relatively understudied despite its critical role in predation attempts, prey evasion, spawning events, and overcoming hydraulic challenges.
Kenneth W. Zillig +9 more
doaj +1 more source
Frontiers in Sports and Active Living, 2022 Sprint performance is critical for endurance performance in sports characterized by multiple accelerations like a cross-country Olympic mountain bike (XCO MTB) race.
Bent R. Rønnestad
doaj +1 more source
Individualisation of time-motion analysis : a method comparison and case report series [PDF]
, 2014 © Georg Thieme Verlag KG. This study compared the intensity distribution of time-motion analysis data, when speed zones were categorized by different methods.
Abt, G. +7 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Sex differences in hypertension and other cardiovascular diseases [PDF]
, 2018 No abstract ...
Currie, Gemma, Delles, Christian
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Multicenter evaluation of TB-SPRINT 59-Plex Beamedex®: accuracy and cost analysis
BMC Infectious Diseases, 2019 Background Molecular tests can allow the rapid detection of tuberculosis (TB) and multidrug-resistant TB (MDR-TB). TB-SPRINT 59-Plex Beamedex® is a microbead-based assay developed for the simultaneous spoligotyping and detection of MDR-TB.
Regina Bones Barcellos +15 more
doaj +1 more source
Learning What We Didn’t Know — The SPRINT Data Analysis Challenge
New England Journal of Medicine, 2017 The SPRINT Challenge brought together teams of clinical trialists and data analysts and demonstrated that when they work together, they can develop new ideas. By building on this common ground, analysts and trialists can reduce the great divide over data sharing.
Nancy S, Burns, Pamela W, Miller
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source