Results 231 to 240 of about 25,618,778 (303)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Optimizing fountain codes for DNA data storage. [PDF]

Comput Struct Biotechnol J
Schwarz PM, Freisleben B.
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Fabio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Primer-Disk-Enabled DNA Data Storage System with Index and Record-Many-Read-Many Features. [PDF]

Adv Sci (Weinh)
Ma J, Yang Y, Pei B, Mi S, Xiong Z, Ouyang L.   +5 more
europepmc   +1 more source

Probe-Based Mechanical Data Storage on Polymers Made by Inverse Vulcanization. [PDF]

Adv Sci (Weinh)
Mann AK, Tonkin SJ, Sharma P, Gibson CT, Chalker JM.   +4 more
europepmc   +1 more source

Composite Mapping for Peptide-Based Data Storage with Higher Coding Density and Fewer Synthesis Cycles. [PDF]

Adv Sci (Weinh)
Zhang A, Wang L, Zhai X, Xiao Y, Wu Y, Zhao Y, Liu K, Zheng JS, Chen D.   +8 more
europepmc   +1 more source

Pantheon-DNA: Versatile encoding-decoding system with integrated adaptive NGS preprocessing algorithms for DNA data storage. [PDF]

Comput Struct Biotechnol J
Leal AG, Aoyagi TY, Costa-Martins AG, de Souza DT, da Silva CMF, Ueda ET, Parada MGO, Feitosa AE, Fujita A.   +8 more
europepmc   +1 more source

Random access and semantic search in DNA data storage enabled by Cas9 and machine-guided design. [PDF]

Nat Commun
Imburgia C, Organick L, Zhang K, Zhang K, Cardozo N, McBride J, Bee C, Wilde D, Roote G, Jorgensen S, Ward D, Anderson C, Strauss K, Ceze L, Nivala J.   +14 more
europepmc   +1 more source

Building and implementation of a common infrastructure for specimen and data storage at an academic medical center. [PDF]

J Clin Transl Sci
Santillan DA, Jacobus LS, Henry MD, Weiner GJ, Winokur PL, Knosp BM, Davis HA.   +6 more
europepmc   +1 more source