Results 121 to 130 of about 42,049,725 (376)

Memory-Efficient Synaptic Connectivity for Spike-Timing- Dependent Plasticity

open access: yesFrontiers in Neuroscience, 2019
Spike-Timing-Dependent Plasticity (STDP) is a bio-inspired local incremental weight update rule commonly used for online learning in spike-based neuromorphic systems.
Bruno U. Pedroni   +8 more
doaj   +1 more source

Crossing the Logarithmic Barrier for Dynamic Boolean Data Structure Lower Bounds

open access: yes, 2017
This paper proves the first super-logarithmic lower bounds on the cell probe complexity of dynamic boolean (a.k.a. decision) data structure problems, a long-standing milestone in data structure lower bounds.
Agarwal Pankaj K.   +4 more
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Information about the Structure of Phthiocerol from Mass Spectral and X-Ray Crystallographic Data. [PDF]

open access: bronze, 1956
Ragnar Ryhage   +4 more
openalex   +1 more source

Data Structure for a Time-Based Bandwidth Reservations Problem

open access: yes, 2003
We discuss a problem of handling resource reservations. The resource can be reserved for some time, it can be freed or it can be queried what is the largest amount of reserved resource during a time interval. We show that the problem has a lower bound of
Brodnik, Andrej, Nilsson, Andreas
core   +2 more sources

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

BRLO-Tree: A Data Structure Used for 3D GIS Dynamic Scene Rendering

open access: yesCybernetics and Information Technologies, 2015
BRLO-Tree (Block-R-Tree-Loose-Octree) is presented in this paper based on the R-Tree and Loose-Octree. The aim of the structure is to visualize the large scale and complex dynamic scenes in a 3D (three-dimensional) GIS (Geographic Information System).
Wang Wenju   +4 more
doaj   +1 more source

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