Results 151 to 160 of about 4,856,518 (315)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Exploring the Application of Large Language Models (LLMs) in Data Structure Instruction: An Empirical Analysis of Student Learning Outcomes in Computer Science

Information
Recent advancements in Large Language Models (LLMs), including ChatGPT, DeepSeek, and Claude, have facilitated their growing integration into computer science education, including data structure courses. Despite their widespread adoption, the association
Hongzhi Li, Lijun Xiao, Kezhong Lu, Dun Li, Zheqing Zhang, Qishou Xia   +5 more
doaj   +1 more source

Community Resource for Innovation in Polymer Technology (CRIPT): A Scalable Polymer Material Data Structure. [PDF]

ACS Cent Sci, 2023
Walsh DJ, Zou W, Schneider L, Mello R, Deagen ME, Mysona J, Lin TS, de Pablo JJ, Jensen KF, Audus DJ, Olsen BD.   +10 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Handling Data Structure Issues with Machine Learning in a Connected and Autonomous Vehicle Communication System

Vehicles
Connected and Autonomous Vehicles (CAVs) remain vulnerable to cyberattacks due to inherent security gaps in the Controller Area Network (CAN) protocol. We present a structured Python (3.11.13) framework that repairs structural inconsistencies in a public
Pranav K. Jha, Manoj K. Jha
doaj   +1 more source

Using Global t-SNE to Preserve Intercluster Data Structure. [PDF]

Neural Comput, 2022
Zhou Y, Sharpee TO.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

On the Importance of Investigating Data Structure in Miniaturized NIR Spectroscopy Measurements of Food: The Case Study of Sugar. [PDF]

Foods, 2023
Gorla G, Taborelli P, Alamprese C, Grassi S, Giussani B.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developing minimum core data structure for the obesity devices Coordinated Registry Network (CRN). [PDF]

BMJ Surg Interv Health Technol, 2022
Long C, Tcheng JE, Marinac-Dabic D, Iorga A, Krucoff M, Fisher D.   +5 more
europepmc   +1 more source