Results 261 to 270 of about 11,430,808 (343)

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

iEEG-BIDS, extending the Brain Imaging Data Structure specification to human intracranial electrophysiology. [PDF]

Sci Data, 2019
Holdgraf C, Appelhoff S, Bickel S, Bouchard K, D'Ambrosio S, David O, Devinsky O, Dichter B, Flinker A, Foster BL, Gorgolewski KJ, Groen I, Groppe D, Gunduz A, Hamilton L, Honey CJ, Jas M, Knight R, Lachaux JP, Lau JC, Lee-Messer C, Lundstrom BN, Miller KJ, Ojemann JG, Oostenveld R, Petridou N, Piantoni G, Pigorini A, Pouratian N, Ramsey NF, Stolk A, Swann NC, Tadel F, Voytek B, Wandell BA, Winawer J, Whitaker K, Zehl L, Hermes D.   +38 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

MEG-BIDS, the brain imaging data structure extended to magnetoencephalography. [PDF]

Sci Data, 2018
Niso G, Gorgolewski KJ, Bock E, Brooks TL, Flandin G, Gramfort A, Henson RN, Jas M, Litvak V, T Moreau J, Oostenveld R, Schoffelen JM, Tadel F, Wexler J, Baillet S.   +14 more
europepmc   +1 more source

Northeast Tibetan Crustal Structure from INDEPTH IV Controlled- Source Seismic Data

, 1970
M. S. Karplus, S. L. Klemperer, Wenjin Zhao, Zhenhan Wu, Danian Shi, Heping Su, L. D. Brown, Chen Chen, J. Mechie, R. Kind, F. Tilmann, Yizhaq Makovsky, R. Meißner   +12 more
openalex   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

A Dynamic Non-Manifold Mesh Data Structure to Represent Biological Materials. [PDF]

J WSCG (Plzen), 2018
Somogyi E.
europepmc   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Using clustered data to develop biomass allometric models: The consequences of ignoring the clustered data structure. [PDF]

PLoS One, 2018
Dutcă I, Stăncioiu PT, Abrudan IV, Ioraș F.   +3 more
europepmc   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source