Results 51 to 60 of about 3,370,595 (309)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Data structures of genome and protein sequences indexing

open access: yesIranian Journal of Information Processing & Management, 2016
Data structure is a tool for storage and retrieval of information which is named logic and mathematic way of specific data organization. various sequences of genes and proteins in various creatures increases the amount of data in genome databases, and ...
Adeleh asadi
doaj  

Framework for the documentation of nature-based solutions for stormwater management

open access: yesBlue-Green Systems, 2023
Nature-based solutions (NBSs) are widely implemented for stormwater management; as such they have become important assets that require proper asset management at different stages of their service life.
Gema Sakti Raspati   +6 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

CONSTRUCTIVE MODEL OF ADAPTATION OF DATA STRUCTURES IN RAM. PART II. CONSTRUCTORS OF SCENARIOS AND ADAPTATION PROCESSES

open access: yesNauka ta progres transportu, 2016
Purpose.The second part of the paper completes presentation of constructive and the productive structures (CPS), modeling adaptation of data structures in memory (RAM).
V. I. Shynkarenko, H. V. Zabula
doaj   +1 more source

Case study: BIM protocol for Skanska (Czech Republic) [PDF]

open access: yesBusiness & IT, 2017
The research paper introduces the problems of technical support of a model in projects in the area of BIM. Planning Requirements (BIM protocol) describe the technical preparedness of models, data repletion, information sharing, communications and other ...
Kvirenc, Patrik, Bouska, Robert
doaj   +1 more source

Oblivious Data Structures [PDF]

open access: yesProceedings of the 2014 ACM SIGSAC Conference on Computer and Communications Security, 2014
We design novel, asymptotically more efficient data structures and algorithms for programs whose data access patterns exhibit some degree of predictability. To this end, we propose two novel techniques, a pointer-based technique and a locality-based technique.
Liu, C   +6 more
openaire   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Superconvergence for optimal control problems governed by semilinear parabolic equations

open access: yesAIMS Mathematics, 2022
In this paper, we first investigate optimal control problem for semilinear parabolic and introduce the standard $ L^2(\Omega) $-orthogonal projection and the elliptic projection.
Chunjuan Hou   +4 more
doaj   +1 more source

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