Results 81 to 90 of about 3,706,151 (258)

The R package for DICOM to brain imaging data structure conversion. [PDF]

Sci Data, 2023
Wulms N, Eppe S, Dehghan-Nayyeri M, Streeter AJ, Bonberg N, Berger K, Sundermann B, Minnerup H.   +7 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Enhanced Framework for Lossless Image Compression Using Image Segmentation and a Novel Dynamic Bit-Level Encoding Algorithm

Applied Sciences
This study proposes a dynamic bit-level encoding algorithm (DEA) and introduces the S+DEA compression framework, which enhances compression efficiency by integrating the DEA with image segmentation as a preprocessing step.
Erdal Erdal, Alperen Önal
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Data visualisation approaches for component network meta-analysis: visualising the data structure. [PDF]

BMC Med Res Methodol, 2023
Freeman SC, Saeedi E, Ordóñez-Mena JM, Nevill CR, Hartmann-Boyce J, Caldwell DM, Welton NJ, Cooper NJ, Sutton AJ.   +8 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Novel Shape Classification Approach Based on Branch Length Similarity Entropy

IEEE Access
This study presents a novel feature vector for shape clustering based on the Branch Length Similarity (BLS) entropy profile, which is invariant to translation, rotation, and scaling, enhancing its effectiveness for shape analysis.
Sang-Hee Lee, Cheol-Min Park
doaj   +1 more source

Genome assembly composition of the String "ACGT" array: a review of data structure accuracy and performance challenges. [PDF]

PeerJ Comput Sci, 2023
Magdy Mohamed Abdelaziz Barakat S, Sallehuddin R, Yuhaniz SS, R Khairuddin RF, Mahmood Y.   +4 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source