Results 191 to 200 of about 37,551,526 (314)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

TypeTaxonScript: sugarifying and enhancing data structures in biological systematics and biodiversity research. [PDF]

open access: yesBiol Methods Protoc
Jordão LSB   +5 more
europepmc   +1 more source

Wheeler graphs: A framework for BWT-based data structures. [PDF]

open access: yesTheor Comput Sci, 2017
Gagie T, Manzini G, Sirén J.
europepmc   +1 more source

Asynchronized Concurrency: The Secret to Scaling Concurrent Search Data Structures

open access: yesInternational Conference on Architectural Support for Programming Languages and Operating Systems, 2015
Tudor David   +2 more
semanticscholar   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy