Results 191 to 200 of about 29,004,461 (256)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Consequences of Misspecifying Levels of Variance in Cross-Classified Longitudinal Data Structures. [PDF]

Front Psychol, 2016
Gilbert J, Petscher Y, Compton DL, Schatschneider C.   +3 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Compile- and run-time approaches for the selection of efficient data structures for dynamic graph analysis. [PDF]

Appl Netw Sci, 2016
Schiller B, Deusser C, Castrillon J, Strufe T.   +3 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

RV Investigator Voyage IN2025_V06 Hydrology Data

Maintenance and Update Frequency: asNeededStatement: Data source: original field data. [ENTER INFORMATION FROM DAP DATA SUBMISSION FORM, SECTION "DATA ACQUISITION" -> "DATA PROCESSING AND ANALYSES"; EXAMPLE:] Nutrient samples were analysed using ...

core  

Stepwise reduction of an asymmetric π-expanded pyracylene towards the crystalline radical trianion. [PDF]

Chem Sci
Zhu Y, Borstelmann J, Neiss C, Wei Z, Görling A, Kivala M, Petrukhina MA.   +6 more
europepmc   +1 more source

Genome alignment with graph data structures: a comparison. [PDF]

BMC Bioinformatics, 2014
Kehr B, Trappe K, Holtgrewe M, Reinert K.   +3 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Fast randomized approximate string matching with succinct hash data structures. [PDF]

BMC Bioinformatics, 2015
Policriti A, Prezza N.
europepmc   +1 more source