Results 31 to 40 of about 14,799,241 (221)
Constraining the Type of Central Engine of GRBs with Swift Data
The central engine of gamma-ray bursts (GRBs) is poorly constrained. There exist two main candidates: a fast-rotating black hole and a rapidly spinning magnetar.
Dai, Zi-Gao+5 more
core +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Dynamic Discovery of Type Classes and Relations in Semantic Web Data
The continuing development of Semantic Web technologies and the increasing user adoption in the recent years have accelerated the progress incorporating explicit semantics with data on the Web. With the rapidly growing RDF (Resource Description Framework)
Ayvaz, Serkan, Aydar, Mehmet
core +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
A Logic for Abstract Data Types as Existential Types [PDF]
The second-order lambda calculus allows an elegant formalisation of abstract data types (ADT's) using existential types. Plotkin and Abadi's logic for parametricity [PA93] then provides the useful proof principle of simulation for ADT's, which can be used to show equivalence of data representations.
Erik Poll, Jan Zwanenburg
openaire +3 more sources
Normal type-2 Fuzzy Rational B-Spline Curve
In this paper, we proposed a new form of type-2 fuzzy data points(T2FDPs) that is normal type-2 data points(NT2FDPs). These brand-new forms of data were defined by using the definition of normal type-2 triangular fuzzy number(NT2TFN).
Gobithaasan, R. U.+2 more
core +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Random Pilot and Data Access in Massive MIMO for Machine-type Communications
A massive MIMO system, represented by a base station with hundreds of antennas, is capable of spatially multiplexing many devices and thus naturally suited to serve dense crowds of wireless devices in emerging applications, such as machine-type ...
Björnson, Emil+4 more
core +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source