Results 41 to 50 of about 14,799,241 (221)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

On the assimilation of SWOT type data into 2D shallow-water models [PDF]

, 2013
In river hydraulics, assimilation of water level measurements at gauging stations is well controlled, while assimilation of images is still delicate. In the present talk, we address the richness of satellite mapped information to constrain a 2D shallow ...
Couderc, Frédéric, Dartus, Denis, Garambois, Pierre-André, Madec, Ronan, Monnier, Jérôme, Villa, Jean-Paul   +5 more
core  

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

SMS design review plan, type 1 data [PDF]

The SMS PDR plan is submitted incrementally 15 days prior to the associated PDR's.

core   +1 more source

A Precision Photometric Comparison between SDSS-II and CSP Type Ia Supernova Data

, 2012
Consistency between Carnegie Supernova Project (CSP) and SDSS-II supernova (SN) survey ugri measurements has been evaluated by comparing SDSS and CSP photometry for nine spectroscopically confirmed Type Ia supernova observed contemporaneously by both ...
Abazajian, Aihara, Aldering, Amanullah, Blondin, Cappellaro, Conley, Contreras, Cooke, D'Andrea, D. P. Schneider, Doi, Ellis, Folatelli, Foley, Foley, Foley, Foley, Freedman, Frieman, G. Folatelli, Ganeshalingam, Gunn, Gunn, Gupta, Hamuy, Hicken, Hoeflich, Hogg, Holtzman, Hsiao, Ivezić, J. Frieman, J. Holtzman, J. Marriner, J. Mosher, Kasen, Kasen, Kelly, Kessler, Kowalski, Krisciunas, L. Corlies, Lampeitl, Lentz, Leonard, Lupton, M. M. Phillips, M. Sako, M. Stritzinger, Mazzali, N. Morrell, Patat, Perlmutter, Pier, Prieto, Quimby, R. Kessler, Riess, Riess, Riess, S. W. Jha, Sako, Schlegel, Smith, Stoughton, Stritzinger, Stritzinger, Sullivan, Suntzeff, Timmes, Tonry, Wang, Wood-Vasey, York   +74 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Improving a data-acquisition software system with abstract data type components [PDF]

data types and object-oriented design are active research areas in computer science and software engineering. Much of the interest is aimed at new software development.
Howard, S. D.
core   +1 more source