Results 81 to 90 of about 44,292,339 (363)
Brain Data Standards - A method for building data-driven cell-type ontologies
Scientific Data, 2023 Large-scale single-cell ‘omics profiling is being used to define a complete catalogue of brain cell types, something that traditional methods struggle with due to the diversity and complexity of the brain.
Shawn Zheng Kai Tan +19 more
doaj +1 more source
Determining cell-type abundance and expression from bulk tissues with digital cytometry
Nature Biotechnology, 2019 Single-cell RNA-sequencing has emerged as a powerful technique for characterizing cellular heterogeneity, but it is currently impractical on large sample cohorts and cannot be applied to fixed specimens collected as part of routine clinical care.
Aaron M. Newman +11 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Recent Neutrino Data and Type III Seesaw with Discrete Symmetry
, 2012 In light of the recent neutrino experiment results from Daya Bay and RENO Collaborations, we study phenomenology of neutrino mixing angles in the Type III seesaw model with an discrete $A_4 \times Z_2$ symmetry, whose spontaneously breaking scale is much
Ahn, Y. H., Kim, C. S., Oh, Sechul
core +1 more source
An Alternative Lambert-Type Distribution for Bounded Data
Mathematics, 2023 In this article, we propose a new two-parameter distribution for bounded data such as rates, proportions, or percentages. The density function of the proposed distribution, presenting monotonic, unimodal, and inverse-unimodal shapes, tends to a positive ...
Héctor Varela +3 more
doaj +1 more source
Integrating diverse genomic data using gene sets
Genome Biology, 2011 We introduce and evaluate data analysis methods to interpret simultaneous measurement of multiple genomic features made on the same biological samples. Our tools use gene sets to provide an interpretable common scale for diverse genomic information.
Svitlana Tyekucheva +3 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Data gathering for science and research
Agricultural Economics (AGRICECON), 2004 Reasoning and argumentation in empirical sciences and research is based on row data and the intermediate and final structures, calculations etc., derived from the raw data.
J. Vaníček
doaj +1 more source
Parametric Compositional Data Types [PDF]
Electronic Proceedings in Theoretical Computer Science, 2012 In previous work we have illustrated the benefits that compositional data types (CDTs) offer for implementing languages and in general for dealing with abstract syntax trees (ASTs). Based on Swierstra's data types la carte, CDTs are implemented as a Haskell library that enables the definition of recursive data types and functions on them in a ...
Bahr, Patrick, Hvitved, Tom
openaire +6 more sources
Pathophysiology of Type 2 Diabetes Mellitus
International Journal of Molecular Sciences, 2020 Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia +7 more
semanticscholar +1 more source