Results 231 to 240 of about 25,665,833 (303)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Effective data visualization strategies in untargeted metabolomics.

Nat Prod Rep
Mildau K, Ehlers H, Meisenburg M, Del Pup E, Koetsier RA, Torres Ortega LR, de Jonge NF, Singh KS, Ferreira D, Othibeng K, Tugizimana F, Huber F, van der Hooft JJJ.   +12 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Meta-analytic rain cloud plots: Improving evidence communication through data visualization design principles. [PDF]

Res Synth Methods
Fitzgerald KG, Khella D, Charles A, Tipton E.   +3 more
europepmc   +1 more source

ImageGP 2 for enhanced data visualization and reproducible analysis in biomedical research. [PDF]

Imeta
Chen T, Liu YX, Chen T, Yang M, Fan S, Shi M, Wei B, Lv H, Cao W, Wang C, Cui J, Zhao J, Han Y, Xi J, Zheng Z, Huang L.   +15 more
europepmc   +1 more source

Biomarkers and Data Visualization of Insulin Resistance and Metabolic Syndrome: An Applicable Approach. [PDF]

Life (Basel)
Sotiropoulos C, Giormezis N, Pertsas V, Tsirkas T.   +3 more
europepmc   +1 more source

Use of Technology in the Rehabilitation Setting: Therapy Observations, Mixed Methods Analysis, and Data Visualization. [PDF]

Arch Rehabil Res Clin Transl
Celian C, Redd H, Smaller K, Ryali P, Patton JL, Reinkensmeyer DJ, Rafferty MR.   +6 more
europepmc   +1 more source