Results 41 to 50 of about 88,910 (290)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CONSIDERATIONS ON REAL TIME DATA WAREHOUSING (RTDW) [PDF]

open access: yesFiabilitate şi Durabilitate, 2014
The RTDW concept originated in the early 2000s. By that time, computing power had increased to a level that was allowing extraction of data collections for reporting purposes.
Marius Bogdan DINU
doaj  

Maximizing the Storage Capacity of Free Cloud Storage Providers

open access: yesRecoletos Multidisciplinary Research Journal, 2016
This study aims to resolve the problem on the free cloud storage services. With innumerable providers, data and files are dispersed across multiple cloud repositories.
Marisa Mahilum Buctuanon   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Meteorological Data Warehousing and Analysis for Supporting Air Navigation

open access: yesInformatics, 2022
Data analysis of weather phenomena to either predict or control human imprint on the environment requires the collection of various forms of observational data ranging from historical and longitudinal to forecast.
Georgia Garani   +3 more
doaj   +1 more source

Graph-based Modelling of Concurrent Sequential Patterns [PDF]

open access: yes, 2010
Structural relation patterns have been introduced recently to extend the search for complex patterns often hidden behind large sequences of data. This has motivated a novel approach to sequential patterns post-processing and a corresponding data mining ...
Chen, Weiru, Keech, Malcolm, Lu, Jing
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Privacy and Confidentiality in an e-Commerce World: Data Mining, Data Warehousing, Matching and Disclosure Limitation

open access: yes, 2006
The growing expanse of e-commerce and the widespread availability of online databases raise many fears regarding loss of privacy and many statistical challenges.
Fienberg, Stephen E.
core   +3 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Enhancing the Search in MOLAP Sparse Data 

open access: yesInformation, 2012
Multidimensional on-line analytical processing (MOLAP) systems deal well with dense data than relational ones (ROLAP). In the existence of sparse data, MOLAP systems become memory consuming, which may limit and slow down data processing tasks.
Joseph Zalaket
doaj   +1 more source

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